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Drug-related problems as a potential cause of hospitalizations
Očovská, Zuzana ; Vlček, Jiří (advisor) ; Trejtnar, František (referee) ; Urbánek, Karel (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Training Workplace Department of Social and Clinical Pharmacy Doctoral Degree Program Clinical and Social Pharmacy Candidate PharmDr. Zuzana Očovská Supervisor prof. RNDr. Jiří Vlček, CSc. Title of Doctoral Thesis Drug-related problems as a potential cause of hospitalizations Introduction and objectives: A drug-related problem is an event or circumstance involving drug therapy that actually or potentially interferes with desired health outcomes. Manifested drug-related problems may contribute to hospital admissions of patients. Such hospital admissions, known as drug-related hospital admissions (DRA), represent a significant and potentially preventable burden on health systems. DRA often arise from the combination of multiple medications, making it important to pay increased attention to drug interactions, particularly in older patients who are taking a larger number of medications. DRA can result from inappropriate medication dosing or the selection of medications in the presence of chronic kidney disease. The main objectives of this thesis are: 1) to determine the prevalence and preventability of DRA and to identify medications and clinical manifestations associated with DRA in patients admitted to hospital via the department of emergency...
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Evaluation of clinical pharmacists interventions in the hospital II
Elbelová, Šárka ; Doseděl, Martin (advisor) ; Babica, Jan (referee)
Evaluation of clinical pharmacists interventions in the hospital III Author: Šárka Elbelová Tutor: PharmDr. Martin Doseděl, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: Considering the constant development of health care it is highly relevant to analyze the contribution of the clinical pharmacist and the potential for further improvement of the drug management. In the theoretical part, special focus is on the phenomenon of physicians' acceptance of recommendations made by clinical pharmacist. It also summarizes the recent studies on this topic. In the following analysis in practical part, the interventions of clinical pharmacist are put under scrutiny as well as the types of the drug-related problems, which are encountered by the clinical pharmacist, the seriousness of these problems and their possible solutions. Furthermore, the physicians' acceptance of recommendations made by clinical pharmacist is measured. Methods: A prospective, descriptive study was conducted in the Nursing Unit of the Department of the Internal Medicine in the Hospital in Olomouc region between October and December 2021. Only newly admitted patients whose pharmacotherapy was revised were considered. The data (age, sex, diagnosis,...
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Evaluation of clinical pharmacists interventions in the hospital II
Elbelová, Šárka ; Doseděl, Martin (advisor) ; Babica, Jan (referee)
Evaluation of clinical pharmacists interventions in the hospital III Author: Šárka Elbelová Tutor: PharmDr. Martin Doseděl, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: Considering the constant development of health care it is highly relevant to analyze the contribution of the clinical pharmacist and the potential for further improvement of the drug management. In the theoretical part, special focus is on the phenomenon of physicians' acceptance of recommendations made by clinical pharmacist. It also summarizes the recent studies on this topic. In the following analysis in practical part, the interventions of clinical pharmacist are put under scrutiny as well as the types of the drug-related problems, which are encountered by the clinical pharmacist, the seriousness of these problems and their possible solutions. Furthermore, the physicians' acceptance of recommendations made by clinical pharmacist is measured. Methods: A prospective, descriptive study was conducted in the Nursing Unit of the Department of the Internal Medicine in the Hospital in Olomouc region between October and December 2021. Only newly admitted patients whose pharmacotherapy was revised were considered. The data (age, sex, diagnosis,...
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Evaluation of clinical pharmacists interventions in the hospital
Veličková, Zuzana ; Doseděl, Martin (advisor) ; Malá, Kateřina (referee)
EVALUATION OF CLINICAL PHARMACIST'S INTERVENTIONS IN THE HOSPITAL Author: Zuzana Veličková Supervisor of the thesis: PharmDr. Martin Doseděl, Ph.D. Charles University, Faculty of Pharmacy in Hradec Králové, Department of Social and Clinical Pharmacy BACKGROUND The Drug-Related Problem is an event or circumstance involving drug therapy that actually or potentially interferes with desired health outcomes.i Pharmaceutical care deals with management of DRPs and its goal is to decrease occurrence of DRP. AIMS The aim of the study was to describe and evaluate the most common DRPs occurring in the selected department in the hospital. DRPs have been detected during reviews of pharmacotherapy by the clinical pharmacist. METHODS The study was carried out in the hospital in Šumperk, at the department of the internal medicine, the nursing section. Data was collected from medical records of hospitalized patients. Patient's characteristics (age, gender), diagnosis, using drugs, selected laboratory markers and drug- related problems were recorded. DRPs have been identified during reviews of the clinical pharmacist. Description and evaluation of DRPs contain its management, acceptation of pharmacist's intervention, evaluation of clinical severity and cost benefit of intervention. The classification of DRPs was...
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Analysis of drug-related problems in a health facility I.
Bahnerová, Michaela ; Malý, Josef (advisor) ; Matoulková, Petra (referee)
Analysis of drug-related problems in a health facility I. Author: Michaela Bahnerová1 Tutor: Josef Malý1 1 Department of Social and Clinical Pharmacy, Charles University in Prague, Faculty of Pharmacy in Hradec Králové Intoduction: Drug-related problems (DRPs) lower the quality of health care and present a risk factor in patient's safety. Objectives: The aim of this thesis is identification, classification and further analysis of DRPs in health care facility. Methods: Revision of pharmacotherapy was performed in health care facility in term 6. 8. - 10. 8. 2012. The pharmaceutical team which contained two pharmacists and diplomant examined health documentation of patients hospitalized in the facility. We collected information from personal, allergic, family, and labor-social anamnesis of patients. This data were noted into electronical database and after revision were DRPs classified and evaluated. The results of DRPs identification were evaluated by frequency analysis. In ten randomly selected patients was described DRPs resolution. Results: In total we noticed medical therapy in 175 patients (61 % women). Average patient's age was 58 years. 482 DRPs were identified. Of the patients, 84 % had DRPs and an average of 2,75 DRPs were recorded per patient. Conclusion: Appearance of DRPs is very frequent and...
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The analysis of pharmacotherapy by patients suffering with DM in Greece I
Kalaitzidis, Georgios ; Vlček, Jiří (advisor) ; Doseděl, Martin (referee)
The analysis of pharmacotherapy by patients suffering with DM in Greece I Author: Georgios Kalaitzidis Tutor: Professor RNDr.Jiri Vlcek,CSc. Department of Social and Clinical Pharmacy, Charles University in Prague, Faculty of Pharmacy in Hradec Kralove. Introduction: The diabetes in developed countries concerns 11% of people over 70 years and is the cause of 3% of total deaths in general population. Aim: The aim of the study was to assess the Pharmacotherapy of Diabetes mellitus type II in a pharmacy of a small town of Greece, Veria. Methods: It is retrospective cross-sectional study, which was conducted in a pharmacy in a small town of Greece, Veria. The study population consists of 60 patients with known Type II diabetes Melitus. The data collection was performed by a self-reported questionnaire, which was created and developed by the researcher and filled by the respondents. Results: The mean age of the sample was 56.5±17.5 years. Most of them were females (n=40). Most of the patients knew their fasting glucose level (93.3%,n=56).Of the patients who knew their fasting glucose level, 36 (64.3%) patients had high fasting glucose level and 20 (35.7%) had physiological fasting glucose level. From all the patients(n=60), some of them visited their physician every 6 months (n=24), and every 3 months...
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Analysis of drug-related problems in a health facility IV.
Šubrtová, Linda ; Malý, Josef (advisor) ; Zimčíková, Eva (referee)
Analysis of drug-related problems in a health facility IV. Author: Linda Šubrtová Tutor: PharmDr. Josef Malý, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction: Increasing use of drugs leads to a growing risk of occurence of drug-related problems. These problems can often endanger patient's health and increase the economic cost of the treatment. However, many of these problems can be prevented by controls and collaboration of all health care subjects. Objective: The aim of this work was to carry out a revision of pharmacotherapy in a rehabilitation health facility and to analyse acquired drug-related problems. Methodology: The collection of data took place from 13 to 15 February 2017 in health facility in the Czech Republic. The review of pharmacotherapy was performed by a three-member team (clinical pharmacist, pharmacist, work researcher). The data obtained from the provided medical records were recorded into the database, which was prepared for the purpose of the pharmacotherapy review. Recorded were: the patient's age and sex, allergic, family, work, social and personal history, physical and laboratory examinations and complete pharmacotherapy, which included over-the-counter drugs and dietary supplements, including dosage...
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Analysis of drug-related problems in a health facility IV.
Šubrtová, Linda ; Malý, Josef (advisor) ; Zimčíková, Eva (referee)
Analysis of drug-related problems in a health facility IV. Author: Linda Šubrtová Tutor: PharmDr. Josef Malý, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction: Increasing use of drugs leads to a growing risk of occurence of drug-related problems. These problems can often endanger patient's health and increase the economic cost of the treatment. However, many of these problems can be prevented by controls and collaboration of all health care subjects. Objective: The aim of this work was to carry out a revision of pharmacotherapy in a rehabilitation health facility and to analyse acquired drug-related problems. Methodology: The collection of data took place from 13 to 15 February 2017 in health facility in the Czech Republic. The review of pharmacotherapy was performed by a three-member team (clinical pharmacist, pharmacist, work researcher). The data obtained from the provided medical records were recorded into the database, which was prepared for the purpose of the pharmacotherapy review. Recorded were: the patient's age and sex, allergic, family, work, social and personal history, physical and laboratory examinations and complete pharmacotherapy, which included over-the-counter drugs and dietary supplements, including dosage...
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Analysis of drug-related problems in a health facility IV.
Šubrtová, Linda ; Malý, Josef (advisor) ; Zimčíková, Eva (referee)
Analysis of drug-related problems in a health facility IV. Author: Linda Šubrtová Tutor: PharmDr. Josef Malý, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction: Increasing use of drugs leads to a growing risk of occurence of drug-related problems. These problems can often endanger patient's health and increase the economic cost of the treatment. However, many of these problems can be prevented by controls and collaboration of all health care subjects. Objective: The aim of this work was to carry out a revision of pharmacotherapy in a rehabilitation health facility and to analyse acquired drug-related problems. Methodology: The collection of data took place from 13 to 15 February 2017 in health facility in the Czech Republic. The review of pharmacotherapy was performed by a three-member team (clinical pharmacist, pharmacist, work researcher). The data obtained from the provided medical records were recorded into the database, which was prepared for the purpose of the pharmacotherapy review. Recorded were: the patient's age and sex, allergic, family, work, social and personal history, physical and laboratory examinations and complete pharmacotherapy, which included over-the-counter drugs and dietary supplements, including dosage...
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Evaluation of clinical pharmacists interventions in the hospital
Veličková, Zuzana ; Doseděl, Martin (advisor) ; Malá, Kateřina (referee)
EVALUATION OF CLINICAL PHARMACIST'S INTERVENTIONS IN THE HOSPITAL Author: Zuzana Veličková Supervisor of the thesis: PharmDr. Martin Doseděl, Ph.D. Charles University, Faculty of Pharmacy in Hradec Králové, Department of Social and Clinical Pharmacy BACKGROUND The Drug-Related Problem is an event or circumstance involving drug therapy that actually or potentially interferes with desired health outcomes.i Pharmaceutical care deals with management of DRPs and its goal is to decrease occurrence of DRP. AIMS The aim of the study was to describe and evaluate the most common DRPs occurring in the selected department in the hospital. DRPs have been detected during reviews of pharmacotherapy by the clinical pharmacist. METHODS The study was carried out in the hospital in Šumperk, at the department of the internal medicine, the nursing section. Data was collected from medical records of hospitalized patients. Patient's characteristics (age, gender), diagnosis, using drugs, selected laboratory markers and drug- related problems were recorded. DRPs have been identified during reviews of the clinical pharmacist. Description and evaluation of DRPs contain its management, acceptation of pharmacist's intervention, evaluation of clinical severity and cost benefit of intervention. The classification of DRPs was...
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